Preparative And Process Chromatography Market is Predicted to Observe a Tremendous Growth, With a CAGR of 11.65% To 2028: Grand View Research Inc.
The global preparative
and process chromatography market
size is expected to reach USD 17.26
billion by 2028, according to a new report by Grand View Research, Inc. It
is expected to expand at a CAGR of
11.65% from 2021 to 2028. High demand for monoclonal antibodies, coupled
with the growing adoption of preparative chromatographic techniques in the
bioprocessing industry, is anticipated to boost the revenue growth in the
market over the forecast period.
Moreover, an increase in the number of
R&D activities in the pharmaceutical and biotechnology industries is
driving the adoption of liquid chromatographic techniques in downstream assays,
resulting in the anticipated market growth. In addition, technological
developments to advance the final product recovery in terms of yield accelerate
and augment the uptake of these techniques across various applications.
Furthermore, expanding application of
these techniques has propelled the key players to make strategic investments to
increase their revenue share in the space. Companies are actively engaged in
the development of new products to meet the changing consumer demands. For
instance, in November 2020, Shimadzu Corporation launched “Advanced i-Series”
HPLC. This is an improved flagship liquid chromatography model to support remote
work.
Chromatography columns are gaining
increasing attention in the global space. Companies involved in prepacked
chromatography columns consistently innovate new products to gain a reputed
market share. Moreover, the integration of preparative chromatography in
COVID-19 vaccine development has created lucrative opportunities for the key
players to capture the untapped avenues of the market.
Preparative chromatographic techniques
are anticipated to register the fastest CAGR throughout the forecast period due
to the increasing application in medical research and the drug approval
process. The food end-use segment is estimated to exhibit the fastest CAGR over
the forecast period owing to the high use of analytical techniques for food
safety and food authentication assessment.
Large-scale integration of liquid chromatographic
techniques in downstream processing, technological advancements, and high
demand for preparative techniques have accelerated the growth in this space.
Increasing demand and approval of monoclonal antibodies in the pharmaceutical
and biotechnology industries are expected to fuel the growth in this space
throughout the forecast period. This can be attributed to the higher
penetration of the service providers in the antibody separation techniques that
are based on chromatographic principles, such as affinity chromatography and
column displacement chromatography.
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Moreover, ongoing research paradigms
for the separation and analysis of monoclonal antibodies using the mild reverse
phase chromatography are anticipated to drive research in this market.
Companies are engaged in the development of flexible and robust platforms for
continuous production of monoclonal antibody products, thereby increasing the
demand for quality control.
Preparative And
Process Chromatography Market Report Highlights
- By product, process chromatography
accounted for the largest revenue share in 2020 owing to the growing
research activities and adoption of automated systems in the field of
biopharmaceuticals
- On the basis of type, the liquid
chromatographic segment dominated the market in 2020 owing to the high
demand for preparative HPLC in the therapeutic development process
- Based on end use, the pharmaceutical
segment held the largest share in 2020 owing to increasing application in
drug safety assessment as an analytical tool for qualitative and
quantitative analysis
- North America dominated the market in
2020 owing to increasing investments in the development of new resin for
the isolation and purification of vaccines. Extensive COVID-19 vaccine
development efforts in the region have spurred the market growth as the
process significantly relies on the use of chromatography for the
characterization
- Asia Pacific is projected to witness the
fastest growth over the forecast period. The growing biopharmaceutical
sector in the region has increased the demand for antibodies and resins.
Extensive R&D activities in the Asian pharmaceutical market result in
the growing demand for chromatography products
Affinity chromatography has emerged as
a pivotal tool to purify proteins as it is based on highly specific
interactions occurring between the protein of interest and an immobilized
ligand. The Downstream Process (DSP) or the product purification process is one
of the costliest aspects of modern bioprocess protocols, particularly with
respect to proteins. Hence, in these cases, chromatography serves as a crucial
tool at all stages of DSP, from early initial capture to the final polishing or
finishing steps.
Preparative techniques have gained
wide acceptance for the purification of APIs and the key drivers associated
with this expanding acceptance include improved throughput, cost-effectiveness,
and purity. These techniques offer the users sufficient material volume at the
desired quality for the initiation of clinical and preclinical trials. This, in
turn, opens alternative routes for commercialization with minimum time invested
in product development.
List of Key
Players of Preparative And Process Chromatography Market
- GE Healthcare
- Agilent Technologies
- Danaher Corporation
- Bio-Rad Laboratories Inc.
- Merck KGaA
- Thermo Fisher Scientific Inc.
- Shimadzu Corporation
- Novasep Holding S.A.S
- Waters Corporation
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