Single-use Bioreactors Market Size Is Poised To Reach $12.06 Billion By 2030: Grand View Research Inc.
The global single-use
bioreactors market size is
expected to reach USD 12.06 billion by
2030, registering a CAGR of 17.19%
from 2023 to 2030, according to a new report by Grand View Research, Inc.
Owing to the rising demand for biopharmaceuticals, coupled with increasing
investments in single-use technologies, the market for single-use bioreactors
is expected to witness significant growth throughout the forecast period.
Furthermore, the COVID-19 outbreak has
positively impacted the market for SUBs. The race to create an effective vaccine
against the SARS-CoV-2 virus is being undertaken by numerous biopharmaceutical
firms. As a result, the need for single-use bioreactors has drastically
increased. For instance, in October 2020, ABEC supplied six 4,000 L single-use
bioreactors to the Serum Institute of India, for the production of COVID-19
vaccines on a large scale at a reasonable cost.
The value of the product, the time
required for product development and production, in addition to the criticality
of the phase are now influencing the industry's propensity to employ single-use
bioreactors. In addition, the medical industry has a significant demand for
these single-use bioreactors. As a result, pharmaceutical companies use these
reactors to make medicines without having to compromise on their quality.
The flexibility of using single-use
bioreactors is one of their main benefits. The growing trend toward multi-drug
facilities necessitates the manufacture of various medications utilizing the
same facility, in the shortest amount of time, and for the least amount of
money. Thus, it will increase the demand for single-use bioreactors and further
fuel market growth.
Additionally, the market for SUBs is
anticipated to increase quickly because of considerable prospects from emerging
countries, the demand for customized medicine, and an anticipated rise in
bio-similar production in the U.S. For instance, around USD 110 billion worth
of biologics were anticipated to lose their patent protection by 2020. The
demand for biosimilars is therefore expected to rise in the coming years as a
result of mounting pressure to lower healthcare costs and regulatory certainty
about biosimilars, further driving the market growth.
However, the administration of
single-use bioreactors-related challenges and worries about leachable and
extractable are most likely to impede the single-use bioreactors market's
expansion over the anticipated time. The single-use bioreactors market is
likely to benefit from new opportunities brought on by license termination and
emerging markets. Despite this, the market is primarily driven by the growing
single-use bioreactor usage among startups and small businesses, technological
developments in SUBs, and the benefits offered by these products.
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Additionally, SUBs have been used more
frequently lately in contemporary biopharmaceutical operations. This is mainly
because of their exceptional capacity to increase flexibility, decrease
investment, and regulate operational expenses. Furthermore, single-use
bioreactors have a wide range of uses in academic and industrial laboratories,
including drug discovery, pharmaceutical, environmental, and life science
research for the production of vaccines, antibodies, cell culture, and
biofuels, among other things. Thus, it will increase demand and further boost
market growth.
Single-use systems are emerging as an
important technology for pharmaceutical and mammalian cell culture
applications. They are particularly well suited for biopharmaceutical
production, where prevailing market trends call for quick, easy, and flexible
deployment.
Single-use
Bioreactors Market Report Highlights
- By product, the single-use bioreactor
systems segment held the dominant share in 2022. The availability of
disposable bioprocess bags in different sizes for a variety of uses,
including the storage of reagents, buffers, sterile medium, sera, and cell
cultures, is predicted to drive the market's expansion
- By type, the stirred tank bioreactors
segment held a larger market share in 2022, driven by the increasing
adoption of stirred tank SUBs from pilot scale to large scale
manufacturing, which is anticipated to boost the market growth in the
forecast years
- Based on the type of cell, the mammalian
cells segment held a larger share in 2022. The segment is being driven by
the increasing usage of single-use bioreactors for mammalian cell culture
in several research studies. This is another key factor expected to drive
market growth significantly in the coming years
- By molecule type insights, the vaccines
segment held a larger share in 2022. This is due to the less expensive
nature and availability in smaller volumes. This allows manufacturers to
test different cell lines as well as growth conditions more quickly and at
a lower cost to improve vaccine manufacturing
- By application insights, the research and
development (R&D)/process development segment held a larger share in
2022. Single-use bioreactors are most commonly used in GMP production,
process development, and research. Furthermore, the growing adoption of
single-use bioreactors in process development is facilitating the market
growth
- By usage insights, the lab-scale production
segment held a larger share in 2022. Various types of waste creation and
bioreactor operations are included in controlled laboratory-scale studies
before scaling up. Due to such advantages offered by lab-scale
bioreactors, the market is expected to grow during the forecast period
- By end-use insights, the CMOs & CROs
segment held a larger share in 2022. CMOs are constantly changing
processing facilities as well as lines, and the more stable product
developers for bioprocessing equipment & facilities. Thus, propelling
the market growth
- North America held the largest market
share in 2022. The North American market is predicted to be driven due to
the presence of key players and the well-established biopharmaceutical
industry in the region
- The major companies providing single-use
bioreactor products operating in the North American region include Danaher
Corporation, Thermo Fisher Scientific, and others, and the presence of a
highly developed healthcare research framework and substantial expenditure
in R&D fuels the market growth in the region
- Asia Pacific is expected to expand at the
highest rate in the forecast period. Factors such as rising investments
and funding initiatives among Asian companies are expected to drive the
market in the region. Furthermore, China is expected to be at the
forefront owing to the high adoption of single-use technology in the
country
During the pandemic, the need for
speedy mass production of vaccines against the SARS-CoV-2 virus saw an upsurge
in the adoption of flexible technologies by biopharmaceutical companies
that could be brought online rapidly. The coronavirus disease and the necessity
for rapid large-scale vaccine manufacturing have caused an increase in demand
for single-use systems, thereby driving the growth of the single-use
bioreactors market.
Moreover, the modular nature of
single-use systems has facilitated local manufacturing in developing countries
that are incapable to afford investments in stainless steel facilities, to
support their own regional and domestic markets. Presently, most bioreactors
available in the market are being used for research related to COVID-19.
In addition, some of the manufacturers
are using bioreactors to culture suitable host cells for the coronavirus, in
order to study the viral pathogenesis in humans. Moreover, in the past few
months, single-use bioreactor manufacturers have undertaken numerous
collaborative initiatives, to develop biologics/vaccines as potential
therapeutics against COVID-19.
List of Key
Players in the Single-use Bioreactors Market
- Sartorius Stedim Biotech
- Thermo Fisher Scientific
- Danaher
- Merck KgaA
- Celltainer Biotech BV
- Getinge AB
- Eppendorf AG
- Cellexus
- PBS Biotech Inc.
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